Faculty of Medicine

Notable Projects

• Evaluation of strategies for the optimal treatment of women with atypical squamous cells of undetermined significance (ASCUS).
• PRECAMA study: molecular subtypes of breast cancer in premenopausal women in Latin America.
• POSCAMA project—evaluation of the association between breast cancer and genetic ancestry, exogenous, and familial risk factors: a multicentric case-control study in four Colombian cities.
• Evaluation of the clinical usefulness of regulatory proteins of the cell cycle and the HPV methylation pattern in the detection of cervical preneoplastic lesions.
• Evaluation of the implementation of the three stages of vaccination (2012-2014) against human papillomavirus for girls born from 2003 to 2005 in the municipality of Manizales, Colombia.
• Identification of differentially expressed microRNA in cervical cancer and cervical preneoplastic lesions: toward a tool for early detection in HPV-positive women.
• ESTAMPA project (Multi-centric cervical cancer screening and triage study with human papillomavirus testing).

Main Research Results

• Comparison of immediate colposcopy, repeat conventional cytology and high-risk human papillomavirus testing for the clinical management of atypical squamous cells of undetermined significance cytology in routine health services of Medellin, Colombia: The ASCUS-COL trial. DOI: 10.1002/ijc.33318. 
• Effective methylation triage of HPV positive women with abnormal cytology in a middle-income country. DOI: 10.1002/ijc.33314.
• Reproductive factors and molecular subtypes of breast cancer among premenopausal women in Latin America: the PRECAMA study. DOI: 10.1038/s41598-018-31393-7.

Research Portafolio