Faculty of Medicine

Notable Projects

• Morphological characterization, molecular tipification, and evaluation of the expression of genes involved in the resistance and allergenic protein production of Aspergillus species isolated from in-hospital and out-of-hospital environments in the Aburrá Valley metropolitan area.
• Implementation of the CRISPR/Cas9 System for gene editing in fungal pathogens.
• Concordance between the estimated biological age with a clinical cardiovascular algorithm and a biomarker-based method.
• E. coli expression of Reteplase, a variant of recombinant Human Plasminogen Tissue Activator.

Main Research Results

• Draft Genome Sequences of Clinical and Environmental Isolates of Aspergillus tamarii from Colombia. DOI: 10.1128/MRA.01514-19
• Updates and Comparative Analysis of the Mitochondrial Genomes of Paracoccidioides spp. Using Oxford Nanopore MinION Sequencing. https://doi.org/10.3389/fmicb.2020.01751
• Genome analysis reveals evolutionary mechanisms of adaptation in systemic dimorphic fungi. ISSN 2045-2322. DOI: 10.1038/s41598-018-22816-6
• Molecular Epidemiology of Candida auris in Colombia Reveals a Highly Related, Countrywide Colonization With Regional Patterns in Amphotericin B Resistance. DOI: 10.1093/cid/ciy411

Research Portafolio