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sábado, 27 de abril 2024
27/04/2024
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Research group

Colombian Chemical Plants

Academic Unit: Faculty of Exact and Natural Sciences

Colombian Ministry of Science

Class

A

Call

894

Profile

OECD

Discipline

Natural sciences

Subdiscipline

Chemical sciences

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Strategic Focus

The group focuses its research on the search for compounds, whether of natural or synthetic origin, with promising biological activity that serve as candidates for the development of new drugs against parasitic diseases (such as leishmaniasis or Chagas disease) and against colorectal cancer. Several of our studies also focus on determining the pharmacological and preventive potential of plant extracts.

Research Areas and Topics

 

  • Medicinal Chemistry: synthesis of biologically active compounds.
  • Natural Products: search for secondary metabolites with pharmacological potential.
  • Computational Chemistry: In Silico, pharmacokinetic studies, molecular Docking and molecular dynamic.
  • Biological Tests: Chemoprevention of Colorectal Cancer.

Sustainable Development Goals (SDGs)

Group Coordinator

Wilson Cardona Galeano PhD in Chemical Sciences.

University of Antioquia.

Group Coordinator Email

wilson.cardona1@udea.edu.co

Scientific Cooperation

Collaborative Relationships

International:

  • Universidad Jaume I, Castellón, España
  • Universidad Nacional Mayor de San Marcos, Lima, Perú
  • Pontificia Universidad Católica de Chile
  • The University of Texas, EEUU

National:

  • Universidad Industrial de Santander
  • Universidad del Tolima
  • Universidad de Santander

Local:

  • Universidad Pontificia Bolivariana
  • Corporación para Investigaciones Biológicas (CIB) 
  • Universidad Nacional sede Medellín

Notable Projects

  • Synthesis of Hybrid Molecules and Determination of their Activity Against Colon Cancer, part of the program: Academic-Scientific Alliance for the Strengthening of HEIs, focused on nanobioengineering for the prevention, diagnosis, and treatment of colon cancer.
  • Synthesis of multi-target molecular hybrids for the treatment of Alzheimer's disease: cellular and enzymatic study.
  • Synthesis and Study of the Anticancer Properties of S-Allyl cysteine Derivatives.

Main Research Results

From the projects and research carried out by the group, more than 50 articles in high-impact journals have been published; 6 PhD and 5 master's students have been trained. To highlight, there is a patent for an absorbent (NC2016/0000271) and another for a synthetic compound as a potential anticancer agent, which is in process. 

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Universidad de Antioquia | Vigilada Mineducación | Acreditación institucional hasta el 2033 | NIT 890980040-8
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