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Genetics, Regeneration and Cancer
AccionesResearch group
Spanish
Genetics, Regeneration and Cancer
Academic Unit: Faculty of Exact and Natural Sciences
OECD
Discipline
Natural sciences
Subdiscipline
Biological sciences
Strategic Focus
To identify the molecular and cellular mechanisms that are involved in cancer and regeneration processes in order to contribute to the transfer of knowledge and technology to develop regenerative medicine therapies for humans.
Research Areas and Topics
- Occupational genotoxicology in populations exposed to industrial carcinogens in Cerro Matoso S.A. and Ecopetrol.
- Microbial genetics.
- Population genetics.
- Toxicological genetics and environmental mutacarcinogenesis.
- Tumor genetics.
- Regenerative medicine.
- Genetically modified microorganisms.
- Analysis on the X chromosome inactivation and its relation to breast cancer.
- Regenerative biology.
- Cell cycle.
- Cytogenetics and anti-cytostatic agents in leukemoid cells.
- DNA damage, repair and oxidative stress.
- Molecular diagnosis in humans.
- Molecular epidemiology of Streptococcus pneumoniae.
- Susceptibility genes in gastrointestinal cancer.
Sustainable Development Goals (SDGs)
Scientific Cooperation
Collaborative Relationships
- Universidad EAFIT, Colombia.
- Universidad CES, Colombia.
- The University of Kentucky, USA.
- Jackson Laboratories, USA.
- Karolinska Institute.
- Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.
Notable Projects
- Identifying molecules with anti-cancer and regenerative potential from Colombian biodiversity amphibians.
- Creation of transgenic salamanders to elucidate regenerative mechanisms such as the loss of a limb.
- Molecular biomonitoring of the genotoxic damage caused by pollution from the Aburra Valley.
- Description of the regenerative process in Colombian salamanders.
- Creation of molecular databases from technological amphibians.
Main Research Results
- Identifying peptides with antimicrobial and anti-cancer potential from Colombian frogs and salamanders.
- Description of regenerative processes on a morphological and cellular level in Colombian salamanders.
- Creation of molecular databases from Colombian salamanders.
- Creation of the first transgenic vertebrate in Colombia.
Research Portafolio
- Cell cycle analysis
- Analysis of proliferation, cytotoxicity, and apoptosis.
- Analysis on the effect of drugs and natural or semi-synthetic compounds.
- Isolation of tissue cell lines or tumors.
- Cytogenetics description and cell lines karyotypes.
- Occupational cytogenetic biomonitoring (mining, refinery, etc.).
- Analysis of the toxicity and genetic effect of drugs and natural or semi-synthetic compounds.
- Citogenotoxicity test for bioactive substances and cosmetics.
- Analysis on oxidative stress in blood cells and cell lines.
- Cytogenetic test on micronucleus.
- In vivo micronucleus test through flow cytometry.
- Chromatid exchange test for alkylating agents or cross-linking agents.
More Information
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AccionesUniversidad de Antioquia | Vigilada Mineducación | Acreditación institucional hasta el 2033 | NIT 890980040-8
Recepción de correspondencia: calle 70 No. 52 - 21 | Apartado Aéreo 1226 | Dirección: calle 67 No. 53 - 108 | Horario de atención
Conmutador: [57 + 604] 219 8332 | Línea gratuita de atención al ciudadano: 018000 416384 | Fax: [57 + 604] 263 8282
Peticiones, quejas, reclamos, sugerencias, denuncias, consultas y felicitaciones
Política de tratamiento de datos personales
Medellín - Colombia | Todos los Derechos Reservados © 2020
Recepción de correspondencia: calle 70 No. 52 - 21 | Apartado Aéreo 1226 | Dirección: calle 67 No. 53 - 108 | Horario de atención
Conmutador: [57 + 604] 219 8332 | Línea gratuita de atención al ciudadano: 018000 416384 | Fax: [57 + 604] 263 8282
Peticiones, quejas, reclamos, sugerencias, denuncias, consultas y felicitaciones
Política de tratamiento de datos personales
Medellín - Colombia | Todos los Derechos Reservados © 2020