Basic and Applied Microbiology Research Group
Academic Unit: School of Microbiology
Medical and health sciences
Through the implementation of different strategies and lines of research, we generate knowledge and participate in scientific training concerning the problem of bacterial resistance from the concept of "one health" (human, animal, and environmental) as well as in the development of alternative therapies and in the study of biology, classification, and identification of important microorganisms for human health.
Research Areas and Topics
- Development and evaluation of diagnostic technologies.
- Molecular epidemiology.
- Host-pathogen interaction.
Sustainable Development Goals (SDGs)
- Center for Discovery and Innovation Hackensack Meridian Health-Nutley New Jersey (USA).
- Division of Infectious Diseases and Vaccinology School of Public Health, University of California (USA).
- Universitat de València (Spain).
- Federal University of Goiás (Brazil).
- University of Sao Paulo (Brazil).
- University of North Carolina (USA).
- Oswaldo Cruz Foundation (Brazil).
- Universidad del Rosario, Bogota.
- Development of a surveillance support system based on molecular epidemiology for the control of carbapenems resistance in Klebsiella pneumoniae, Pseudomonas aeruginosa, Acinetobacter baumanni, and Enterobacter cloacae in high complexity care institutions in the city of Medellin.
- Transplantation of lung and bone marrow-derived stem cells as a therapy for the control of experimental pulmonary fibrosis process induced by Paracoccidioides brasiliensis.
- Morphological characterization, molecular typing, and evaluation of the gene expression involved in the resistance and production of allergenic proteins of Aspergillus species isolated from in-hospital and out-of-hospital environments of the Aburrá Valley metropolitan area.
Main Research Results
- Generation of new knowledge through the publication of more than 80 scientific articles in high-impact journals. Participation in the training of master's and doctoral students. Contribution to local knowledge concerning the epidemiology of bacterial resistance, validation of molecular methodologies for the study of resistance mechanisms and the surveillance of resistant bacterial clones.
- Standardization and implementation of molecular techniques that allow the acquisition of modified microorganisms for later study; and additionally, implementation of animal models and cell cultures for the study of the pathogenesis of some microorganisms and the development of alternative therapies for the treatment of some infectious diseases.
- Epidemiological surveillance support service: Molecular identification of clinical and environmental bacterial and fungal isolates, determination of genetic relationships (outbreak studies), detection of antibiotic resistance mechanisms.
- Expert epidemiological advicee.
- Evaluation of antimicrobial effectiveness.
- Training: Diploma course in antimicrobial resistance.
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